Snap-8 10mg

SNAP-8 Cosmetic Peptide 

Sequence: Acetyl-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH₂
Molecular Formula: C₄₁H₇₀N₁₆O₁₆S
Molecular Weight: 1075.16 g/mol

Overview
SNAP-8 is a synthetic octapeptide derived from the N-terminal domain of the SNAP-25 protein. It functions by competing with native SNAP-25 for incorporation into the SNARE complex, subtly modulating neurotransmitter release at neuromuscular junctions. This controlled modulation results in decreased muscle contraction intensity, helping to soften expression lines and visibly reduce wrinkle depth.

Key Research-Based Benefits
• Demonstrated to diminish the appearance of dynamic wrinkles, particularly those on the forehead and periocular region.
• Considered a safer, less invasive, and more economical alternative to botulinum-based treatments—achieving comparable outcomes through a distinct biochemical pathway.
• Formulated for inclusion in advanced topical systems such as serums, emulsions, and gels to target localized areas of concern.

Formulation and Stability
INCI Name: Acetyl Glutamyl Heptapeptide-1
Active Content: 0.05 % SNAP-8 Powder

SNAP-8 is produced via precision peptide synthesis followed by lyophilization to yield a stable polymorphic crystalline powder. Minor variations in crystal morphology are normal and do not affect product integrity. It is available as either a reconstitutable powder or a ready-to-use aqueous solution (0.5 g/L). For optimal peptide stability, it should be incorporated at the final compounding stage below 40 °C. Inclusion levels of 3 – 10 % of the aqueous solution in finished formulations are typically recommended to achieve measurable anti-wrinkle activity.

Storage and Shelf Life
Both powder and solution forms should be stored in a cool, dark, and hygienic environment. At ambient conditions, shelf life is approximately 12 months; refrigeration at 4 °C extends stability to 18 months or longer. Occasional preservative precipitation in refrigerated solutions may occur but does not compromise product quality.

Disclaimer
All information provided by America 1st Peptides is intended solely for scientific and educational purposes. Products are supplied exclusively for in vitro research and analytical applications. They are not approved by the FDA for therapeutic, diagnostic, or human/animal use of any kind.